Pondostatural evolution in patients with Celiac Disease

Authors:

Kirchschläger E^a, Camps Rubiol T^b, Valverde Gómez F^c, Hernández Lorca MA^d, Roldán Martín MB^e, Ramos Fernández JM^f, Mendienta Sanz E^g

Reference of this article.:

Kirchschläger E, Camps Rubiol T, Valverde Gómez F, Hernández Lorca MA, Roldán Martín MB, Ramos Fernández JM y cols. Evolución ponderoestatural en pacientes con enfermedad celiaca. Rev Pediatr Aten Primaria. 2000;2:559-571..

Published in Internet: 31/12/2000

Abstract:

Celiac disease is a permanent intolerance to gluten , in which genetic, environmental and immunologic factors are implicated. Still there are doubts about the exact pathogenesis. A variable failure to thrive is a dominant feature. Removal of gluten from the diet leads to clinical remission and catch-up of weight and height. In this study we realize a follow-up of growth y weight patterns of 14 celiac patients, from birth up to 12 months after instauration of gluten free diet (GFD). We observe a low weight and normal size at birth; the introduction of gluten produces a mean decrease of 0.11 scores of standard desviation (SDS) of weight and a loss of 0.23 SDS of height. Weight catch-up was already significant after 3 months of GFD, while the percentiles of height did not initiate revovery until 3 months after the elimination of gluten. After a year of GFD mean weight gain is 1.16 SDS and the mean height gain is 0.60 SDS. We related the catch-up with the age at diagnosis and evaluated the weight/height ratio and the major growth velocity.

Keywords: Celiac disease. catch-up growth. Gluten-free-diet.

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