Vol. 28 - Num. 109

Clinical Reviews

Majocchi’s Granuloma: Clinical Presentation and Management Challenges in Infants

M.ª Fernanda Echeverría Croccoa, Bárbara Pizarro Stankeb, Daniela Castroa, Nicolás Arcos Castroc

aFacultad de Medicina. Universidad de los Andes. Santiago. Chile.
bResidente Pediatría. Universidad de los Andes. Santiago. Chile.
cFacultad de Medicina. Universidad Diego Portales. Santiago. Chile.

Correspondence: MF Echeverría. E-mail: fecheverriacrocco@gmail.com

Reference of this article: Echeverría Crocco MF, Pizarro Stanke B, Castro D, Arcos Castro N. Majocchi’s Granuloma: Clinical Presentation and Management Challenges in Infants . Rev Pediatr Aten Primaria. 2026;28:[en prensa].

Published in Internet: 20-03-2026 - Visits: 8

Abstract

Majocchi’s granuloma is a rare form of deep dermatophytosis caused by fungal invasion of the hair follicle and dermis. While typically reported in adults, often after inappropriate topical corticosteroid use, its occurrence in infants is exceptional and represents a significant diagnostic challenge. We report the case of an infant with persistent erythematous-squamous plaques unresponsive to conventional topical therapies. Diagnosis was confirmed by mycological culture, which demonstrated dermatophyte growth. The patient achieved complete resolution with systemic terbinafine. This case underscores the importance of considering Majocchi’s granuloma in the differential diagnosis of chronic skin lesions in children and highlights the value of early recognition and prompt initiation of systemic antifungal therapy to prevent therapeutic delays.

Keywords

Dermatophytosis Differential diagnosis Granuloma Terbinafine