Vol. 28 - Num. 110

Evidence based Pediatrics

Is at-home administration of ondansetron useful after an emergency visit in children with gastroenteritis?

Sara Suárez Cabezasa, Enrique Llerena Santa Cruzb

aServicio de Pediatría. Hospital Virgen de Altagracia. Manzanares. Ciudad Real. España
bCAP La Torrassa. L’Hospitalet de Llobregat. Barcelona. Hospital Joan XXIII. Tarragona. España.

Reference of this article: Suárez Cabezas S, Llerena Santa Cruz E. Is at-home administration of ondansetron useful after an emergency visit in children with gastroenteritis? . Rev Pediatr Aten Primaria. 2026;28:255-8. https://doi.org/10.60147/f7ff233e

Published in Internet: 23-06-2026 - Visits: 498

Abstract

Authors’ conclusions: among children with gastroenteritis-associated vomiting, the administration of ondansetron after a pediatric emergency department visit was associated with a decreased risk of moderate-to-severe gastroenteritis in the following 7 days compared to placebo.

Reviewers’ commentary: despite a well-designed and methodologically sound study, the data on home ondansetron in cases of acute gastroenteritis have not demonstrated a sufficiently relevant impact to warrant changes to current clinical practice.

Keywords

Antiemetics Gastroenteritis Ondansetron